Preheat oven to 375°F. Line a rimmed baking sheet with aluminum foil or parchment paper.
Pat salmon fillets completely dry with paper towels and place on prepared baking sheet.
In a small bowl, whisk together melted butter, honey, lime juice, lime zest, and minced garlic until well combined.
Season salmon with salt and pepper on both sides, then pour honey lime garlic butter mixture evenly over each fillet.
Bake for 15-18 minutes until salmon flakes easily with a fork. For caramelized top, broil for last 2-3 minutes, watching closely.
Let rest 2-3 minutes, garnish with fresh parsley, and serve with lime wedges.